Sixteen Alpha Hydroxyestrone

This estrogen deserves its own private blog. I will give homage to this killer estrogen. I mentioned in a previous blog entry that 16 alpha hydroxyestone is derived from estrone through the conversion enzyme CYP1B1. This enzyme has been found in high concentations in prostate and breast cancer tissue. It becomes active when stimulated to develop in increased quantities by its substrate (estrone). Although estrone is made naturally in the body of men and women it is contained in very high amounts in water soluble dairy products ( fat free dairy products).

What makes it such a dangerous estrogen is the fact that it binds to estrogen receptors alpha (bad) and it binds in such a fashion as to almost never dissociate from this receptor. It is a major stimulant of cell growth and is likely the estrogen of concern in causing cancer of the breast, prostate and ovaries.

Now let me tell you a very interesting and true story. A major university respected for the quality of its faculty and research production performed a study in Mongolia. Teenage men and women wer given certain quantities of milk over a one month period. These test subjects were chosen because they almost never consume dairy. All known estrogen levels in blood and urine were measured before and during the milk consumption test. These researchers were about to write a paper concerning their results. I became involved when a friend of theirs and mine called me and expressed concern that they may have misinterpreted their data. My friend arranged a four way call between these researchers, myself and my friend and an estrogen metabolite expert retired from this same prestigous university. The two researchers were about to claim that dairy was safe because the blood levels of estrone dropped in the test subjects during the course of the study. I had examined their data with their permission and realized that they had made a critical error in interpretation of their data. Although the estrone levels had dropped, the 16 alpha hydroxyestrone levels had increased dramatically. It became immediately apparent taht the estrone dropped because it had been converted into the very dangerous estrogen: 16 alpha hydroxyestrone.The retired estorgen metabolism PhD agreed. So their you have it, when humans consume milk, they convert the dairy estrogens into a carciogenic estrogen.

16 alpha hydroxyestrone has also been implicated in the development of autoimmune diseases. What a nightmare!

A person can help their autoimmune diseases by stopping dairy consumption and consuming Kudzu. Kudzu stimulates an enzyme called CYP1A1 that converts estrone into a "good" estrogen known as 2-hydroxyestrone. Start your path to better health. Stop consuming dairy now! Get to the health food store and buy Kudzu capsules. Take 1000 mg ,four a day.-Robert D. Bibb, M.D.